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Hereditary spastic paraplegias (HSPs) comprise a group of heterogeneous inherited-neurological diseases characterized by spasticity and lower limb weakness. On the other hand, HSP presents a high level of clinical and genetic heterogeneity with an obvious overlap with other neurodegenerative or metabolic disorders that makes HSP diagnosis very challenging.

Hearing loss (HL) is an etiologically heterogeneous disorder that affects around 5% of the world's population and is expected to affect almost 2.5 billion individuals by 2050. Over the years, with the advancement of technology and the use of methods such as Linkage analysis and Next-generation sequencing, other valuable studies have been conducted at the Genetic Research Center of the University of Social Welfare and Rehabilitation Sciences. A research aimed at discovering novel hearing loss genes in Iranian deaf families using ES was conducted at this center and led to the discovery of eight novel candidate genes.

Since the outbreak of coronavirus in the Iran, the Genetics Research Center of the University of Social Welfare and Rehabilitation Sciences decided to study the transmission of the virus to Iran by obtaining different strains of Covid-19 virus. The results were published in April 2021 in an article entitled "SARS-CoV-2 outbreak in Iran: The dynamics of the epidemic and evidence on two independent introductions "published in the journal "Transboundary and Emerging Diseases".

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