23/09/2017
آمار بازدید
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 online : 2
Dr. Afagh Alavi
 

Afagh Alavi

PhD            Cell & Molecular Biology, University of Tehran

MSc.           Cell & Molecular Biology, University of Tehran

Assistant Prof.

e-mail: afaghalavi@gmail.com

           afaghalavi@ut.ac.ir

Tel. No.: 0098-21-22180138

Address: Genetics Research Center- University of Social Welfare and Rehabilitation- Kudakyar Alley- Daneshju Blvd.- Evin- Tehran- Iran

Link in scopus: http://www.scopus.com/authid/detail.url?authorId=19639734300

Link in google scholar: https://scholar.google.com/citations?user=gNsa34UAAAAJ&hl=en

 

Research Interests:

I interested in neuromuscular disorders such as Amyotrophic lateral sclerosis (ALS), Limb Girdle Muscular dystrophy (LGMD), Facioscapulohumeral muscular dystrophy (FSHD), Pantothenate kinase-associated neurodegeneration (PKAN), PLA2G6-associated neurodegeneration (PLAN), Hereditary Motor Sensory Neuropathy (HMSN) and Parkinson' disease (PD).

I had also been involved in several other important projects such as investigation of genetic of Ichthyosis, Niemann-Pick disease (NPC) and eye diseases (Glaucoma and corneal dystrophies). Recently, I have focused on the genetic of muscular dystrophies.

 

Current Projects:

  • Genetic analysis of Iranian patients affected to FSHD; facioscapulohumeral muscular dystrophy.
  • Clinical and genetic study of 40 Iranian patients affected to Limb girdle muscular dystrophy type sarcoglycopathy.
  • Genetic analysis of Iranian patients affected to Parkinson' disease.

 

Selected publications:

Alavi A, Nafissi S, Rohani M, Zamani B, Sedighi B, Shamshiri H, Fan JB, Ronaghi M, Elahi E. Genetic analysis and SOD1 mutation screening in Iranian amyotrophic lateral sclerosis patients. Neurobiol Aging. 2013; 34(5):1516.e1-8.

Alavi A, Nafissi S, Shamshiri H, Malakooti Nejad M, Elahi E. Identification of mutation in NPC2 by exome sequencing results in diagnosis of Niemann-Pick disease type C. Mol Genet Metab. 2013; 110(1-2): 139-144

Ansari Dezfouli M, Alavi A, Rohani M, Rezvani M, Nekuie T, Klotzle B, Tonekaboni SH, Shahidi GA, Elahi E. PANK2 and C19orf12 mutations are common causes of neurodegeneration with brain iron accumulation. Mov Disord. 2013; 28(2):228-32.

Alavi A, Nafissi S, Rohani M, Shahidi GA, Zamani B, Shamshiri H, Safari I, Elahi E. Repeat expansion in C9ORF72 is not a major cause of ALS among Iranian patients. Neurobiol Aging. 2014; 35(1): 267.e1e267.e7

Alavi A, Shamshiri H, Nafissi S, Khani M, Klotzle B, Fan J, Steemers F, Elahi E. HMSN-P caused by p.Pro285Leu mutation in TFG is not confined to patients with Far East ancestry. Neurobiol Aging. 2015; 36: 1710-1716

more

 

http://genetic.uswr.ac.ir/index.jspindex.jsp?fkeyid=&siteid=60&fkeyid=&siteid=60&pageid=9769

 

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