Welcome from the Center Director
PhD: University of London, King's College London (UK)
MD: Shaheed Beheshti University of Medical Sciences (Iran).
Tel. No.: 0098-21-22180138
Address: Genetic Research Center- University of Social Welfare and Rehabilitation- Kudakyar Alley- Daneshju Blvd.- Evin- Tehran- Iran
Dr. Ohadi is currently working on the evolutionary aspect of short tandem repeats (STRs) in the core promoter interval of protein-coding genes, by implementing comparative genomics and gene expression studies. Her goal is to fund a workable argument on a possible role of STRs in speciation and evolution in human and non-human primates.
Namdar-Aligoodarzi P, Mohammadparast S, Zaker-Kandjani B, Talebi Kakroodi S, Jafari Vesiehsari M, Ohadi M. Exceptionally long 5' UTR short tandem repeats specifically linked to primates. Gene. 2015 Sep 10;569(1):88-94.
Rezazadeh M, Gharesouran J, Mirabzadeh A, Khorram Khorshid HR, Biglarian A, Ohadi M. A primate-specific functional GTTT-repeat in the core promoter of CYTH4 is linked to bipolar disorder in human. Prog Neuropsychopharmacol Biol Psychiatry. 2015 Jan 2;56:161-7.
Ohadi M, Valipour E, Ghadimi-Haddadan S, Namdar-Aligoodarzi P, Bagheri A, Kowsari A, Rezazadeh M, Darvish H, Kazeminasab S. Core promoter short tandem repeats as evolutionary switch codes for primate speciation. Am J Primatol. 2015 Jan;77(1):34-43.
Mohammadparast S, Bayat H, Biglarian A, Ohadi M. Exceptional expansion and conservation of a CT-repeat complex in the core promoter of PAXBP1 in primates. Am J Primatol. 2014 Aug;76(8):747-56.
Ohadi M, Mohammadparast S, Darvish H. Evolutionary trend of exceptionally long human core promoter short tandem repeats. Gene. 2012 Oct 1;507(1):61-7.
The human genome is highly variable and each individual’s genome contains approximately 3.5 million Single Nucleotide Polymorphisms (SNPs) and 1000 large (>500 bp) Copy Number Variations (CNVs).
Today, large scale projects such as the 1000 Genomes and the International HapMap projects have been implemented on large scale samples from different populations such as Europeans, Americans, East Asians, and sub-Saharan Africans to increase our understanding of the contribution of genomic variations to human diseases. … more